The legendary Great Smoky Mountains National Park conjures up images of classic blue silhouette of mountain ridges, black bears, elk, and rolling waterfalls.
Something you'll learn is that most road trips will include a combination of the Great Smoky Mountains National Park itself and the surrounding towns and cities that flank it on both sides of Tennessee and North Carolina.
If you're flying in and out of the region, you'd be better off renting from the airport than trying to find a city location. This would be a lot more efficient than having to find ways into and out of the city.